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Pharmaceutical terms explained - Page 4

December 5, 2013

Spirits

Spirits are alcoholic or hydroalcoholic solutions of volatile substances. Generally, the alcoholic concentration of spirits is rather high, usually over 60%. Because of the greater solubility of aromatic or volatile substances in alcohol than in water, spirits can contain a greater concentration of these materials

October 8, 2013

Pharmaceutical Equivalents/ Alternatives/ Substitution

Pharmaceutical Equivalents Drug products in identical dosage forms that contain the same

August 17, 2013

API – Active Pharmaceutical Ingredient

The U.S. Food and Drug Administration (FDA) is the government agency that

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Fault Tree Analysis (FTA)

October 20, 2013

The Fault Tree Analysis tool is an approach that assumes failure of the functionality of a product or process. This

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Failure Mode Effects Analysis (FMEA)

October 16, 2013

Failure Mode Effects Analysis provides for an evaluation of potential failure modes for processes and their likely effect on outcomes

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Dosage Forms

October 14, 2013

As pure compounds, drugs are usually solid substances (amorphous or crystalline) or, in rare cases, liquids. Drugs are combined with

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Buffered Solutions & Buffer Capacity

October 14, 2013

A buffered solution is one that resists changes in its pH when small amounts of acid or base are added,

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pH of Pharmaceutical Systems

October 14, 2013

The pH of body fluids ranges between 1 and approximately 8. The stomach is the most acidic region of the

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Bioequivalence

October 14, 2013

An extension of the concept of relative bioavailability, which essentially involves comparing the total amounts of a particular drug that

Pharmaceutical Articles

Bioequivalence Study (How are two chemically equivalent drug products called bioequivalent?)

October 14, 2013

An extension of the concept of relative bioavailability, which essentially involves comparing the total amounts of a particular drug that

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Absolute and Relative Bioavailability Definitions

October 12, 2013

Absolute Bioavailability The absolute bioavailability of a given drug from a dosage form is the fraction (or percentage) of the

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Disintegrants

October 12, 2013

Disintegrants are required to break up capsules, tablets and granules into primary powder particles in order to increase the surface

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Molecularity

October 12, 2013

Molecularity is the number of molecules involved in forming the product. This follows from the balanced (stoichiometric) equation describing the

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